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IV.4.2. HONEY BEE THERAPEUTIC PRODUCTS, HUMAN CELL AND EXTRACELLULAR ENVIRONMENT

 

When the human health is discussed, this, namely the discussion, will invariably slip into the disease and diseases. Any issues would include this discussion, which can be as many as diseases and body organ should be treated, the medicine will always group them in two major problems, including all the others: prophylaxis and therapy.

If the diseases are the result of the accumulated cellular dysfunction that may cause the dysfunction of one or more organs, then they need to prevent the deterioration of the cells, as the one of the extracellular environment, too. The history, symptoms and appropriate medical investigations may indicate the progress towards disease and before its onset, preventive measures can be taken. They are the cheapest and most beneficial ones, subject to the qualification of the one who has prescribed them, but also in that of adherence (compliance) of the one who are prescribed for. It is not the place to make a much needed comprehensive analysis of the prophylaxis. The prevention of the onset of the disease, of one or another body organ, however, can not be done outside the prevention of the destabilization of the structure and functions of the cell and the extracellular environment. Likewise, the rehabilitation of the functions of a certain organ and the remission of the diseases which have already begun are not possible without the functional rebalancing of the cell and the extracellular environment.

The medical biochemistry, as the molecular and cellular biology have vanguard tasks in the human medicine, tasks which are amplified when it evolves into biomedicine. The medical act, whatever it may be, requires the knowledge of the human cells and therapeutic substances that can restore the functional balance.

The cell is the fundamental unit of the human body as it is a system in relation to the subsystems it is made up of and in relation to the tissue, the body organ in the structure of which the tissue is included being a subsystem. Its functions are multiple - information, software, self-regulation, heterogeneity, completeness, etc…

The human body consists of about 2,000 billion of cells (Cotrutz et al., 2011), which have many similarities but also some differences regarding the shape, dimensions, features etc. The human cell construction, the cell protection and the homeostasis of the extracellular environment (MEC), need the biochemical offer of the nature.

 Studying a large variety of offers of the biochemical point of view, I have concluded the need for them to be complementary (diversified), as the imbalances are due either to the lack of the necessary of the morpho-functional point of view elements to the living matter - at the level of the macronutrients, biostimulants and protective factors or to the imbalance between the biochemical elements of the offer at both quantitatively and qualitatively levels.

Table No. 2. Offer of Honey Bee Therapeutic Products for Biostructure of Human Cell

HUMAN CELL

CELLULAR STRUCTURES                 

EXTRACELLULAR MATRIX            

* membraneous lipids - their precursors or biomolecules of:

    -cholesterol

    -phospholipids  - phosphoglycerides: choline, phosphatidylcholine, serine, inositol

                                 - sphyngolipids: sphyngomyelin, gangliosides, cerebrosides

    -glycolipids        -    galactocerebrosides, glycocerides etc.

* membraneous proteins: as amino-acids precursor of fibrillar, globular proteins

* carbohydrate       -     all the precursors    

                             -    biomolecules: oligosaccharides, proteoglycans, glycoproteins, glycolipids

GLICOCALIX

MEMBRANE

MITOCHONDRIA

  * biomolecules of phospholipids for membranes

   * all enzymes - including MAO, coenzyme A, ATP-es, SOD, etc.).

   * coenzymes - including Q10

   * ions: Ca2 +, Mg2 +, Mn2 +, Fe2 +, etc..

   * acids, including DNA and RNA

   * glucose etc.

LYSOSOMES

 * membraneous constituents - glycoproteic

 * acid hydrolases - phospholipase, glicosidase, proteases, lipases, nucleases

PEROXISOMES

 * membraneous constituents

* enzymes - catalase and oxidases

ENDOPLASMIC RETICULUM

* membrane phospholipids - precursors or biomolecules  

* glycoproteins

* ionized calcium

* enzymes : precursors and biomolecules of: NADH, ATP-es glucose-6-phosphatase

GOLGI COMPLEX

*  membraneous constituents

*  precursors - carbohydrates, lipids, proteins

* biomolecules such as those secreted - polyosides, glycoproteins, lipoproteins

NUCLEUS

   * phospholipids and membraneous proteins: precursors and biomolecules of -

      * perinuclear enzymes and Ca2 +

      * DNA and RNA molecules

    * chromatin-biomolecules precursors of basic and acidic proteins, lipids, ions

      * receptors for steroid hormones, etc.

EXTRACELLULAR MATRIX

   * precursors: amino-acids, carbohydrates

    * biomolecules: glycosaminoglycans, proteoglycans

Selective adaptation.( Cotrutz et al., 20011; Haulică,2009; Mărghitaș, 2005, 2007; Atanasiu, 2005; Ayres et al., 1993; Bankova et al., 1989, 1992, 2002; Bonga et al., 1983; Canini et al., 2007; Chiriță, 2009; Ciplea et al., 1991; Andrițoiu, 2006, 2009)

Through the researches undertaken within the Apiteherapy Medical Center, we have found and highlighted by studies already published that the bee products and thereby, the honey bee therapeutic products that we produce, contain, fact unique to any other allopathic or complementary therapeutic means, all the substances to be foud out in the human cell structure.

We compared the biostructure of the human living - at the cell and extracellular environment level - with the biochemical structure of the bee products. In this way we found and placed at axiom level the conclusions:

1) the bee makes the most complete and balanced transmission of substances fromn nature to man;

2) the honey bee therapeutic products contain all the components of the human cell, as well as those necessary to its functions or its protection, which explains their immunomodulator potential;

3) the honey bee therapeutic products contain biomolecules identical to those produced by the real factory which is the human cell, which are necessary for its physiological functions or being exocitated into  the extracellular environment;

4 ) the  biochemical offer of the honey bee therapeutic products includes both the precursors necessary for the human metabolism and biocompatible biomolecules, fact of a  particular importance in cases of malfunctions.

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